Informations du cours

You will be expected to know:

- How to draw the structure of standard and modified pyrimidine and purine bases,

Watson-Crick base pairs, and simple nucleotide chains.

- The forces that stabilize higher order structure of nucleic acids.

- The relative differences between A, B, and Z DNA helical forms.

- Reactivity of nucleic acids to heat, pH, nucleases, and specific chemicals.

- Common techniques and reagents used to detect, synthesize, and modify nucleic acids